pentobarbital will decrease the level or outcome of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the extent or impact of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will lower the level or effect of rolapitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Long-expression coadministration of powerful CYP3A4 inducers with rolapitant may possibly significantly reduce rolapitant efficacy.
CYP3A4 inducers may perhaps boost the metabolism of clopidogrel to its Lively metabolite. Check clients for possible increase in antiplatelet results when CYP3A4 inducers are utilized together with clopidogrel
pentobarbital will decrease the extent or impact of atorvastatin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
lasmiditan, pentobarbital. Possibly improves outcomes of one other by sedation. Use Warning/Watch. Coadministration of lasmiditan together with other CNS depressant medicines, such as Liquor have not been evaluated in scientific scientific tests. Lasmiditan may cause sedation, and other cognitive and/or neuropsychiatric adverse reactions.
pentobarbital and olopatadine intranasal both of those improve sedation. Stay away from or Use Alternate Drug. Coadministration raises hazard of CNS depression, which can cause additive impairment of psychomotor efficiency and bring about daytime impairment.
pentobarbital will reduce the extent or effect of paclitaxel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will lower the extent or result of conjugated estrogens, vaginal click here by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Warning when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone may perhaps boost and may result in perhaps lethal respiratory depression
pentobarbital will lessen the level or effect of bazedoxifene/conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or impact of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. The efficacy of hormonal contraceptives may very well be lessened. Usage of a nonhormonal contraceptive is suggested.
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Contraindicated (one)pentobarbital will minimize the level or result of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism.